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Study in mice suggests stem cells could ward off glaucoma

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Eye medical doctors use quite a lot of assessments to catch indicators of glaucoma. Early detection and immediate therapy can stop imaginative and prescient loss, however the situation i s power and should be monitored for all times. Credit score: Steven E. Smith An infusion of stem cells may assist restore correct drainage for fluid-clogged eyes in danger for glaucoma. That is the upshot of a research led by a Veterans Affairs and College of Iowa staff. Researchers led by Dr. Markus Kuehn injected stem cells into the eyes of mice with glaucoma. The inflow of cells regenerated the tiny, delicate patch of tissue referred to as the trabecular meshwork, which serves as a drain for the eyes to keep away from fluid buildup. When fluid accumulates within the eye, the rise in stress may result in glaucoma. The...

Tuned gels reveal molecules that drive stem cell differentiation

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This exhibits molecular gels with tunable stiffness used to direct stem cell destiny. Credit score: Alakpa et al./Chem 2016 By monitoring stem cell differentiation on gels that mimic the stiffness and nanofibrous construction of organic tissue, researchers have recognized the particular molecules that stem cells use when deciding on bone and cartilage fates. When fed to straightforward stem cell cultures, these molecules (largely lipid and ldl cholesterol metabolites) have been then discovered to information stem cells to generate desired cell sorts. The examine, which exhibits how new biomaterials can take the guesswork out of figuring out elements that drive stem cell differentiation, seems on July 27 in  Chem  -- Cell Press's first bodily science journal. Researchers have identified that the s...